Scorching heat across the U.S. already has caused more than a dozen deaths in Texas alone and led to mounting misery from the Pacific Northwest to the South

It’s hard to argue a better way to kick off summer than with 2023 Miami Swim Week. Having taken place in early June, the Paraiso runway shows and Summer Fashion Summit showcased the biggest emerging swim trends and need-to-know designers for the beach season ahead.

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It appears that Saweetie has taken her latest fashion inspiration from the Stone Age. On 12 September, the “Best Friend” rapper attended the 2023 MTV Video Music Awards (VMAs) in a pink, sequin gown featuring a halter neck and her hair pulled back into a sleek pony. However, it was the two oversized bones attached to the dress that seemed to capture everyone’s attention. As she posed for photos on the “pink” carpet outside the Prudential Center in Newark, New Jersey, one bone appeared to be tied to her collar, while the other was tied at the waist. The unique dress first debuted in Area’s Fall Winter 2023 collection, which contained several designs full of bones, fur, and animal patterns. While hosting the MTV VMAs pre-show, Saweetie - whose real name is Diamonté Quiava Valentin Harper - explained the reasoning behind her eye-catching look. “The inspiration behind this is fashion when it first started: Cavemen,” she said. Saweetie also appeared to be having fun on the red carpet with her caveman-inspired dress, even kissing the bone in one photo. However, it wasn’t just the “ICY GRL” singer who joined in on the fun. In fact, many people took to X - formally known as Twitter - where they cracked jokes about Saweetie’s VMAs look. Unsurprisingly, a number of awards show viewers compared the rapper’s outfit of choice to something from The Flintstones. “Saweetie looks like a Flintstone,” joked one person on X. “Is she wearing the Fred Flintstone collection?” said someone else. “Are the VMAs being held in Bedrock?” a third user wrote. Despite some critics, many fans still complimented Saweetie’s caveman-inspired outfit. “Saweetie look like a Icy Flintstone,” said one user. “I loveeeee her #VMA”. “Saweetie looks soo cute I love her makeup,” another fan wrote. In addition to Saweetie, there were many other memorable fashion moments at this year’s MTV VMAs. Doja Cat wore a barely-there, white Apocene dress that closely resembled spider webs. Her look featured sparse, white fabric draped across her body, with a pair of nude underwear hidden underneath the ensemble. Meanwhile, VMAs host Nicki Minaj took wedding fashion to a whole new level when she arrived in a pink, corset bodysuit with a sheer, lace skirt and a dramatic vail. Taylor Swift leads this year’s nominees with eight nods, followed closely by “Kill Bill” singer SZA, who holds six nominations. Doja Cat, Kim Petras, Miley Cyrus, Nicki Minaj, Olivia Rodrigo and Sam Smith are tied at five nominations, and BLACKPINK, Diddy and Shakira each received four. The full list of VMA winners can be found here. Read More 2023 MTV VMAs: The best-dressed stars on the red carpet, from Olivia Rodrigo to Doja Cat 2023 MTV VMA winners list in full – live updates Taylor Swift is channeling her Reputation era in stunning black dress at 2023 MTV VMAs Taylor Swift is channeling her Reputation era in stunning black dress at MTV VMAs 2023 MTV VMAs: The best-dressed stars on the red carpet Cardi B wears dress made entirely of hair clips on 2023 VMAs red carpet

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In our series Salary Stories, women with long-term career experience open up about the most intimate details of their jobs: compensation. It’s an honest look at how real people navigate the complicated world of negotiating, raises, promotions and job loss, with the hope it will give young people more insight into how to advocate for themselves — and maybe take a few risks along the way.

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Ex-New Zealand Prime Minister Jacinda Ardern announced Friday she will write a book about leadership to be published worldwide, after five tumultuous years in...

Alcohol addiction ruins millions of lives every year, but scientists may have found a cure for this terrible affliction. A new treatment for alcohol use disorder (AUD) has been trialled in monkeys with impressive results and, if these translate to human trials, the impact could be monumental. A team of neuroscientists and physiologists from across the US tested a new type of gene therapy to see if they could directly target the underlying brain circuitry associated with sustained heavy drinking. As they noted, in the journal Nature Medicine, people suffering from AUD commonly return to alcohol use even if they attempt to quit. This is largely to do with what’s known as mesolimbic dopamine (DA) signalling – meaning how the central nervous system circuit communicates the feelgood neurotransmitter dopamine. A protein called glial-derived neurotrophic factor (GDNF) is key to keeping these neurons in this reward circuitry functioning. However, experts have found that levels of GDNF are reduced in people with AUD during periods of alcohol abstinence, most notably in a region of the brain called the ventral tegmental area (VTA), as IFLScience notes. Therefore, the researchers decided to test whether using gene therapy to deliver more GDNF to the VTA could help reinforce this crucial dopaminergic signalling and prevent patients from suffering an alcoholic relapse. The team of scientists explained how alcohol consumption in non-addicts prompts the release of dopamine, creating a pleasurable buzz feeling, but chronic alcohol use causes the brain to adapt and stop releasing so much dopamine. “So when people are addicted to alcohol, they don’t really feel more pleasure in drinking,” Dr Kathleen Grant, a senior co-author of the study, said in a statement. “It seems that they’re drinking more because they feel a need to maintain an intoxicated state.” For their research, Dr Grant and her colleagues used eight rhesus macaque monkeys, who were exposed to increasing concentrations of alcohol over four 30-day “induction” periods. The monkeys then had free access to alcohol and water for 21 hours a day for six months, during which they developed heavy drinking behaviours. This was then followed by a 12-week abstinence phase, with the GDNF treatment performed four weeks in for half of the subjects. The gene therapy was delivered using a a viral vector containing a copy of the human GDNF gene injected directly into the primate’s VTA, according to IFLScience. And the results were truly jaw-dropping. “Drinking went down to almost zero,” Dr Grant said. “For months on end, these animals would choose to drink water and just avoid drinking alcohol altogether. They decreased their drinking to the point that it was so low we didn’t record a blood-alcohol level.” The most exciting aspect of their findings is the suggestion that gene therapy could offer a permanent solution for people with the most severe cases of AUD. This will be a welcome glimmer of hope to many, given that some 29.5 million people were diagnosed with AUD in the US alone in 2021, according to the National Institute on Alcohol Abuse and Alcoholism. Of these 29.5 million sufferers, almost a million (894,000) were aged between 12 and 17. It’ll likely be some time before we know for sure whether the gene therapy can be rolled out in humans, but it’s an important first step in tackling this devastating disorder. Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.