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Consistently sleeping less than five hours a night could increase the risk of depression, research suggests. Poor sleep has been considered a side-effect of mental ill health in the past, but the new study found that the link between sleep and mental illness is more complex. People with a stronger genetic predisposition to short sleep – less than five hours in a given night – were more likely to develop depressive symptoms over four to 12 years, the study led by UCL researchers found. But those with a greater genetic predisposition to depression were not more likely to have short sleep. Using genetic susceptibility to disease, we determined that sleep likely precedes depressive symptoms, rather than the inverse Lead author Odessa Hamilton The experts also found that the link was not exclusive to those who were genetically inclined towards sleeping for shorter periods, and people who regularly dozed for five hours or less – without the genetic association – were also more likely to have depression. Lead author Odessa Hamilton, UCL Institute of Epidemiology and Health Care, said: “We have this chicken or egg scenario between suboptimal sleep duration and depression, they frequently co-occur, but which comes first is largely unresolved. “Using genetic susceptibility to disease, we determined that sleep likely precedes depressive symptoms, rather than the inverse.” Researchers used genetic and health data from 7,146 people recruited by the English Longitudinal Study of Ageing (ELSA), with an average age of 65. Short and long sleep durations, along with depression, are major contributors to (the) public health burden that are highly heritable Senior author Dr Olesya Ajnakina Analysis of genetic and health data suggested that short sleep was associated with the start of depressive symptoms, like feeling sad or lonely. Senior author Dr Olesya Ajnakina, UCL Institute of Epidemiology and Health Care and the Institute of Psychiatry, Psychology and Neuroscience at King’s College London, said: “Short and long sleep durations, along with depression, are major contributors to (the) public health burden that are highly heritable. “Polygenic scores, indices of an individual’s genetic propensity for a trait, are thought to be key in beginning to understand the nature of sleep duration and depressive symptoms.” When looking at non-genetic associations between depressive symptoms and sleep duration, the researchers also found that people sleeping five hours or less were 2.5 times more likely to develop depressive symptoms. And people with signs of depression were a third more likely to suffer from short sleep. Suboptimal sleep and depression increase with age, and with the worldwide phenomenon of population ageing there is a growing need to better understand the mechanism connecting depression and a lack of sleep Professor Andrew Steptoe The study, published in Nature, Translational Psychiatry, also revealed a link between sleeping long and developing depressive symptoms. According to the findings, people who slept for more than nine hours were 1.5 times more likely to develop depressive symptoms than those who sleep an average of seven hours. However, depressive symptoms were not associated with sleeping longer four to 12 years later, which corresponded to the genetic findings. Professor Andrew Steptoe, head of Behavioural Science and Health, UCL Institute of Epidemiology and Health Care, said: “Suboptimal sleep and depression increase with age, and with the worldwide phenomenon of population ageing there is a growing need to better understand the mechanism connecting depression and a lack of sleep. “This study lays important groundwork for future investigations on the intersection of genetics, sleep, and depressive symptoms.” People enrolled in the study had an average of seven hours’ sleep a night. More than 10% slept for less than five hours a night at the start of the study period, rising to more than 15% at the end of the study. The proportion of people classed as having depressive symptoms increased by about three percentage points, from 8.75% to 11.47%. In the study, data on sleep and depressive symptoms were combined from two Elsa surveys conducted two years apart, as sleep duration and depression are known to fluctuate over time. Sleep duration and depression are both partly inherited from one generation to the next. Earlier studies have suggested depression is about 35% heritable, and that genetic differences account for 40% of the variance in sleep duration. Read More World Osteoporosis Day: The risk factors and early warning signs everyone needs to know about How to support a child with a stammer From colourful gowns to drones, these wedding trends are set take over 2024 Call The Midwife ‘should come with a health warning’ Halloween: 10 wicked ways to kit out your haunted house Black magic: Go back to black this season with the catwalk-inspired trend

The boho-chic trend is back for fall, and its carefree, free-flowing silhouette is soon to be a favorite dress style for the cooler months. Patterned styles in gemstone shades nestle perfectly within the autumn fashion aesthetic, where they can be paired with ankle boots, sneakers, and jean jackets. Plus, all the layering options make boho dresses a fun piece to have in rotation.

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1. Boden Knit Spot Slipper Boden has come up with some fabulous slipper designs this season and these polka-dot ones are bound to make you smile, even on the greyest of mornings. The faux-fur lining will keep you cosy and the knitted outer is available in different colours. £29 www.boden.co.uk 2. Jack Wolfskin Cloud Ten These are as durable as they are warm, which makes them great for people who are always on the go, even inside. Made primarily from wool felt, the footbed is made from a robust microfibre material and they are available in the suitably manly colours of dark steel or black. £30 www.jack-wolfskin.co.uk 3. M&S Cable Knit Pom-Pom Slippers Now that the mornings are getting colder, girls will love popping these comfy, festive-coloured slippers on when they get out of bed. With a side pom-pom and bow feature, there’s also some fake-fur detail on these slippers. From £10 www.marksandspencer.com 4. UGG Ascot These simple-yet-stylish slippers are the epitome of laid-back luxury. Made from full-grain leather, with a sheepskin lining, they are also light. Available in black or brown, your feet won’t thank you for ever having to take them off. £100 www.uggaustralia.co.uk 5. White Stuff Woof Woof Mule No need to suffer the cold with these comfy mules, complete with a tartan sausage motif and soft faux-fur linings. Light, snugly and rustic, just looking at them will make you want to slip into your PJs and dressing gown and relax. £19.95 www.whitestuff.com 6. Fat Face Logan Check Duvet True to their name, these really do feel like you’re back under the duvet. With a suede outsole and textile upper, they will even keep your ankles warm and if there’s too much colour going on for you, simply opt for the grey-and-white ones instead. £25 www.fatface.com 7. Mothercare Gruffalo Slippers He has terrible tusks and terrible claws... Kids will love acting out their favourite Julia Donaldson tale with these fantastic slippers that will keep little feet warm as toast. Buy them soon and you can take advantage of Mothercare’s special offer on multiple buys. £10 www.mothercare.com 8. The White Company Inuit Slippers It’s hard to find slippers as snug as these. With a shaggy new lining, which also features on the seams, these slipper-boots can be worn full length to keep ankles and calves as warm, or you can roll them down to reveal the faux fur. They’re machine washable, too. £38 www.thewhitecompany.com 9. Just Sheepskin Kensington Knit Just Sheepskin slippers are among the comfiest on the market. These ones, which are available in four different colours, have a slip-resistant sole and as the brand name suggests, it’s made using 100 per cent sheepskin. The only downside is that they combine two sizes into one. £50 www.justsheepskin.com 10. Cormia Men’s Travel Slippers Produced from 100 per cent leather, these slippers have become something of a footwear sensation. Not only are they designed to completely mould to your foot shape and walking style, but they can be folded neatly and compactly into your bag for when you travel. £45 www.thepyjamastore.com

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