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Nicole Byer is many things: an actor, an author, a comic, a podcaster, a historic Emmy winner, and an expert judge of amateur baking, just to name a few. Now, she’s adding another accomplishment to the list: swimwear designer. Launching on July 18, the Nicole Byer x Kitty and Vibe collaboration consists of 12 pieces in three different prints (or “vibes,” in KV parlance).

Our eyesight is often something we take for granted – until there’s something wrong with it. Problems like short-sightedness (myopia) are rapidly increasing. In fact, research has predicted that by 2050 there will be 4,758 million people with the condition – nearly half (49.8%) of the world’s population – as experts are highlighting ahead of National Eye Health Week (September 18-24) In addition, new research by Macushield found 73% of Brits notice their eyes deteriorating with age, and the World Health Organisation’s (WHO) World Report on Vision has predicted a dramatic increase in the need for eyecare in the near future, pointing out that at least 2.2 billion people globally have a vision impairment – and around half of these have vision impairment that could have been prevented. “Some people may not be giving their eye health the attention it deserves, occasionally missing out on annual eye tests, which play a crucial role in detecting conditions like cataracts, glaucoma, and age-related macular degeneration,” says ophthalmologist Dr Jørn Slot Jørgensen. “When identified and addressed in a timely manner, these issues can be managed effectively, helping safeguard our vision.” Jørgensen says the pandemic also played a role in worsening eye problems, particularly the increase in short-sightedness. “With the shift to remote work, people are now more likely to spend extended hours with their screens for work and leisure,” he says. “Prioritising eye health isn’t just a matter of convenience, it’s a fundamental aspect of our overall wellbeing.” Here Jørgensen, of the Laser Eye Clinic London, and Evelyn (Evie) Mensah, a consultant ophthalmologist and eye surgeon at Central Middlesex Hospital and member of The Royal College of Ophthalmologists council, outline seven ways people may be damaging their vision, without even realising… 1. Skipping eye tests Mensah says it’s advisable for people to have a sight test every two years, or more often if their optometrist recommends it. Jørgensen adds: “Failing to schedule regular eye tests can result in undiagnosed eye conditions. Conditions like glaucoma, diabetic retinopathy, and macular degeneration often develop without noticeable symptoms in their early stages, but early detection through eye tests is crucial for effective treatment and vision preservation.“ Routine eye tests can also pick up early signs of underlying systemic health conditions, such as diabetes, high cholesterol and high blood pressure. 2. Prolonged screen time The widespread use of digital devices such as laptops, tablets and smartphones has led to extended periods of screen time for both work and leisure, says Jørgensen. “This can result in digital eye strain, characterised by symptoms like dry eyes, headaches and blurred vision,” he explains. “In this age of digital technology, it’s advisable to relieve digital eye strain by using the 20-20-20 rule,” says Mensah – this means every 20 minutes, looking at something 20ft away for 20 seconds. “In addition, remember to blink when using a screen to prevent eyes from getting dry.” 3. Not wearing UV protective sunglasses Jørgensen says failing to wear sunglasses with adequate UV protection can lead to harmful UV radiation exposure, which may contribute to conditions like cataracts and age-related macular degeneration (AMD). “Protecting your eyes from UV rays, particularly in sunny conditions, is essential for preserving long-term eye health,” he stresses. Mensah says UV exposure can also increase the development of growths on the surface of the eyes called pterygia, and warns: “Not all sunglasses filter UV light, so ensure they carry the CE, UV 400 or British Standard Mark. And never look directly at the sun because this can cause a solar burn in the macula that can result in permanent visual loss.” 4. Poor diet and lack of nutrients Eating a healthy, balanced diet could help reduce your risk of sight-threatening eye disease such as AMD, which impacts central vision. Mensah explains that the macula – part of the retina which processes what you see directly in front of you – contains natural pigments such as lutein and zeaxanthin that are found in dark-green, leafy vegetables such as spinach and kale. “Vitamins A, C and E are also helpful, so eat at least five portions of fruit and vegetables a day,” she advises. “And if you have a family history of AMD, ask your GP about taking nutritional supplements.” Jørgensen adds: “A poor diet lacking essential nutrients like vitamins A, C, and E, as well as minerals like zinc, can harm eye health, as these nutrients are vital for vision and overall eye function. To maintain healthy eyes, it’s crucial to consume a balanced diet rich in leafy greens, colourful fruits and vegetables, and omega-3 sources.” 5. Smoking If you’re a smoker, stopping is not only beneficial to your general health but also your eyes, says Mensah: “Smoking cessation is a modifiable factor that can reduce the risk of developing certain eye conditions such as AMD and cataracts.” Ask your GP for support if you are keen to quit – there are lots of helpful resources available. 6. Not wearing prescribed glasses Mensah says there’s a widespread misconception that wearing prescribed glasses worsens your eyesight. “This notion is inaccurate,” she stresses. “The primary reason for wearing prescribed glasses is simply because you require them. If you neglect to wear them, you run the risk of experiencing headaches.” 7. Inadequate lighting “Working or reading in areas with insufficient lighting can make your eyes work harder, leading to eye strain, discomfort, and poorer vision,” says Jørgensen. He points out that good lighting, often called ‘task lighting’, is vital for creating comfortable conditions for reading and working. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Celebrities mingle with royals at glam Vogue World party in London Sienna Miller bares baby bump at celebrity and royal-studded Vogue event See plus-size model Ashley Graham stun in Old Hollywood-inspired Harris Reed LFW show

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Alcohol addiction ruins millions of lives every year, but scientists may have found a cure for this terrible affliction. A new treatment for alcohol use disorder (AUD) has been trialled in monkeys with impressive results and, if these translate to human trials, the impact could be monumental. A team of neuroscientists and physiologists from across the US tested a new type of gene therapy to see if they could directly target the underlying brain circuitry associated with sustained heavy drinking. As they noted, in the journal Nature Medicine, people suffering from AUD commonly return to alcohol use even if they attempt to quit. This is largely to do with what’s known as mesolimbic dopamine (DA) signalling – meaning how the central nervous system circuit communicates the feelgood neurotransmitter dopamine. A protein called glial-derived neurotrophic factor (GDNF) is key to keeping these neurons in this reward circuitry functioning. However, experts have found that levels of GDNF are reduced in people with AUD during periods of alcohol abstinence, most notably in a region of the brain called the ventral tegmental area (VTA), as IFLScience notes. Therefore, the researchers decided to test whether using gene therapy to deliver more GDNF to the VTA could help reinforce this crucial dopaminergic signalling and prevent patients from suffering an alcoholic relapse. The team of scientists explained how alcohol consumption in non-addicts prompts the release of dopamine, creating a pleasurable buzz feeling, but chronic alcohol use causes the brain to adapt and stop releasing so much dopamine. “So when people are addicted to alcohol, they don’t really feel more pleasure in drinking,” Dr Kathleen Grant, a senior co-author of the study, said in a statement. “It seems that they’re drinking more because they feel a need to maintain an intoxicated state.” For their research, Dr Grant and her colleagues used eight rhesus macaque monkeys, who were exposed to increasing concentrations of alcohol over four 30-day “induction” periods. The monkeys then had free access to alcohol and water for 21 hours a day for six months, during which they developed heavy drinking behaviours. This was then followed by a 12-week abstinence phase, with the GDNF treatment performed four weeks in for half of the subjects. The gene therapy was delivered using a a viral vector containing a copy of the human GDNF gene injected directly into the primate’s VTA, according to IFLScience. And the results were truly jaw-dropping. “Drinking went down to almost zero,” Dr Grant said. “For months on end, these animals would choose to drink water and just avoid drinking alcohol altogether. They decreased their drinking to the point that it was so low we didn’t record a blood-alcohol level.” The most exciting aspect of their findings is the suggestion that gene therapy could offer a permanent solution for people with the most severe cases of AUD. This will be a welcome glimmer of hope to many, given that some 29.5 million people were diagnosed with AUD in the US alone in 2021, according to the National Institute on Alcohol Abuse and Alcoholism. Of these 29.5 million sufferers, almost a million (894,000) were aged between 12 and 17. It’ll likely be some time before we know for sure whether the gene therapy can be rolled out in humans, but it’s an important first step in tackling this devastating disorder. Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

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In Scandinavia, we are famous for our cinnamon and cardamom buns, made with a soft, yeasty dough,” says Trine Hahnemann, author of Simply Scandinavian. “I decided to try them with rhubarb in place of the spices, since it is a local vegetable for me. Just like the original, these buns are soft, sweet and sticky.” Rhubarb sticky buns Makes: 14-16 Ingredients: For the buns: 300g rhubarb 100g caster sugar 50g fresh yeast, or 10g fast-action dried yeast 200ml lukewarm whole milk 100g full-fat crème fraîche 1 egg, lightly beaten 650g strong white flour, plus more to dust 1 tsp sea salt flakes 100g salted butter, softened For the filling: 100g salted butter, softened 50g caster sugar 100g marzipan, grated Method: 1. Cut the rhubarb into one-centimetre pieces, place in a saucepan with 50 grams of the sugar and bring to the boil. Cook for five minutes, then drain through a sieve placed over a heatproof bowl. Return the juice to the pan, bring to the boil once more and cook down until you have a syrup. Leave to cool. 2. Dissolve the yeast in the lukewarm milk in a bowl, then stir in the crème fraîche and egg. Next, mix in the flour, the remaining 50 grams of sugar and the salt. Knead the butter, little by little, into the dough, then knead well on a floured work surface until smooth. 3. Put the dough in a bowl, cover with a tea towel and let it rise for one to two hours, or until doubled in size. 4. Make the filling by mixing the butter, sugar and marzipan into a smooth paste. 5. Line some baking sheets with baking parchment. 6. Tip the dough out on to a floured work surface and roll it into a rectangle measuring about 40 x 30 centimetres. Spread the filling evenly over half the dough, then arrange the cooked rhubarb pieces on top of the filling. Fold the plain side over the filled side, then cut across into two-centimetre strips. 7. Take each strip and twist it, then roll each twist into a spiral. 8. Place the rhubarb buns on the prepared trays, pressing down on each so they spread slightly. Cover and leave to rise for 30 minutes. 9. Preheat the oven to 180C/350F/gas mark 4. 10. Bake the pastries for 25-30 minutes, then remove from the oven and brush with the rhubarb syrup. Leave to cool on a wire rack before serving. ‘Simply Scandinavian’ by Trine Hahnemann (Quadrille, £27). Read More Budget Bites: Three light recipes that sing of summer What the hell is Scandinavian food? Lighter fish pie: Comfort food you won’t feel guilty for eating How to make Norwegian potato pancakes Three quick and easy plant-based fakeaways to create at home The Union Rye, review: Finally, a decent restaurant in this charming East Sussex town

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