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Women with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) tend to have more symptoms and co-occurring conditions than men, according to the world’s largest study of the disease. The study, entitled DecodeME, reveals women who have the condition for more than 10 years are more likely to experience increasingly severe symptoms as they get older. ME/CFS is estimated to affect more than 250,000 people in the UK, of all ages and from all social and economic backgrounds. Its key feature, called post-exertional malaise, is a delayed dramatic worsening of symptoms following minor physical effort. Other symptoms include pain, brain fog and extreme energy limitation that does not improve with rest. Causes are unknown and there is currently no diagnostic test or cure. Experts from the University of Edinburgh analysed anonymous survey questionnaires from more than 17,000 people with ME/CFS. Two-thirds of women, and slightly more than half of men, reported at least one active co-occurring condition. Similarly, 39.2% of women and 28.6% of men reported at least one inactive co-occurring condition. We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started Professor Chris Ponting of the University of Edinburgh A condition was considered active if the participant had experienced symptoms in the preceding six months. The most common active co-occurring condition was irritable bowel syndrome, with clinical depression, fibromyalgia, anaemia and hypothyroidism also featuring prominently. Women also reported, on average, more symptoms than men – 42 compared with 36. The most common of these symptoms were brain fog – a term commonly used to describe the cognitive impairment experienced by participants – unrefreshing sleep and muscle pain. These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected Sonya Chowdhury, chief executive of Action for M.E Participants were also asked to define the severity of their illness from mild to very severe using definitions from the UK’s National Institute for Health and Care Excellence guidelines. Experts identified that being a woman and having ME/CFS for more than 10 years are risk factors for severe illness, with symptoms increasing in intensity as they age. Professor Chris Ponting, study lead from the MRC human genetics unit at the University of Edinburgh’s Institute of Genetics and Cancer, said: “ME/CFS is a devastating disease affecting a UK population the size of Derby. “We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started. “Our hope is that DecodeME’s genetic results will shed light on why certain groups are more susceptible to ME/CFS than others.” Sonya Chowdhury, chief executive of Action for M.E. and chair of the management group of the study, said: “These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected. “It’s important to also recognise the impact that it has on men who have ME/CFS and we thank the 20,000 men and women who have already signed up to take part in this very important study. “We still need more to join us, so if you are 16 or older, live in the UK and have a diagnosis of ME/CFS, please do take part now to help us decode ME at www.decodeme.org.uk/portal.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live 4 hacks to get teens off the sofa and get active – as study warns of heart damage Taking adult education classes may lower risk of dementia, study suggests Indiyah Polack: I didn’t want to go on Love Island because of my acne

By Corina Pons and Helen Reid BARCELONA/LONDON In a warehouse on the outskirts of Barcelona, women stand at

Katharine McPhee has revealed that she and husband David Foster have suffered a “horrible family tragedy”. The singer, 39, shared a statement to Instagram on 11 August to announce that she’ll be missing the rest of her husband’s tour in Asia, where she’s been performing as a guest, due to a family emergency. Although she didn’t specify what the tragedy was, she wrote that she’ll be heading home to be with her loved ones, while implying that her husband will still be doing the shows this weekend. “Dearest Jakarta fans, it’s with heavy heart I announce I have to miss our final two shows of our Asian run,” she wrote. “David and I have had a horrible tragedy in our family and at least one of us needs to get back home to our family.” She concluded: “Please know how sorry I am and how much I wish to return someday and perform for you all. Love, Katharine.” Many friends and fans of the couple took to the comments of McPhee’s post to send her kind messages amid the family tragedy. “Sending my love and prayers for your family,” Masked Singer judge Nicole Scherzinger wrote, while Linda Thompson added: “Sending you and David love, & hoping that everything is okay.” “Sending you loads of love. I’m thinking of you guys,” Amanda Kloots also wrote. Foster, 73, is still set to play at the Sentul International Convention Centre in Jakarta, Indonesia, on 11 August and 12 August, according to his official website. He will then be on a hiatus from his tour, before returning to the stage on 1 November in Warren, Michigan. The Independent has contacted a representative for McPhee and Foster for comment. Foster and McPhee made their official debut as a couple in 2018, before officially tying the knot the next year. They welcomed their first child, Rennie, in February 2021. Since then, they have continued to post about their son on social media, hinting that he also has a musical side. In June, Foster shared a video on Instagram of Rennie playing the drums, alongside the caption: “PROGRESS!! Two years three months.” During an interview with Entertainment Tonight in October, Foster acknowledged that although his youngest child has developed an interest in drumming, it’s still soon to tell if he’ll become a musician like his parents. “You know when you look at somebody like Andre Agassi and Steffi Graf, their kids are very talented... but they’re not tennis players, so we don’t know,” he said “He’s so young.” McPhee also agreed, adding: “It makes sense that he’d be musical, but we’re not really sure. He’s certainly obsessed with the drums! Or imaginary drums, for that matter.” Read More Katharine McPhee reveals whether she and David Foster want more children David Foster opens up about raising a toddler at age 73 Katharine McPhee defends husband David Foster after backlash over postpartum body comment Gemma Atkinson slams trolls who called her ‘fat’ just three weeks after giving birth Mother diagnosed with cystic fibrosis, anorexia and incurable cancer 7 ways for parents and carers to ease back-to-school worries

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Sofia Richie Grainge announced her fashion collection SRG is being delayed to autumn 2024 to ensure it is "perfect".

From a hefty fine on a bookshop for selling a novel on which a hit Netflix series is based, to curbing the pension rights of transgender women, Hungary is toughening measures against the LGBTQ community...

San Antonio Spurs guard Devonte’ Graham has pleaded guilty to a driving while intoxicated charge stemming from a July 2022 speeding stop