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How to Take Pictures of Fireworks: 7 Tips to Get the Best Images
How to Take Pictures of Fireworks: 7 Tips to Get the Best Images
A good fireworks photo can be quite striking, but it can also be very tough
2023-07-01 21:55
The Best Smart Kitchen Appliances for 2023
The Best Smart Kitchen Appliances for 2023
If you love cooking and technology, connected appliances and kitchen devices are ideal gadgets for
2023-11-29 06:54
Continued struggles will leave Mercedes frustrated and confused – Martin Brundle
Continued struggles will leave Mercedes frustrated and confused – Martin Brundle
Lewis Hamilton’s “frustrated and confused” Mercedes team are in survival mode, leading Formula One pundit Martin Brundle has claimed. Hamilton finished fourth, two places ahead of team-mate George Russell, at Sunday’s Belgian Grand Prix, while Red Bull’s Max Verstappen wrapped up his eighth straight win. Although Mercedes are second in the constructors’ championship heading into the sport’s summer break, Hamilton appears no closer to ending his 35-race losing streak. The seven-time world champion was also dealt a major blow in Spa-Francorchamps after an upgrade – which included new sidepods and a revised floor – appeared to contribute to the return of porpoising. Speaking after the race, Hamilton said his Mercedes was bouncing “everywhere” and said the sensation was reminiscent of last year’s car – a machine which carried him to the poorest championship finishing position of his career. “Mercedes will be very frustrated,” said Brundle, 64. “Their car is on a knife edge to set up, to understand and to drive. “They are surviving the season, as they did last year, and making the best of a bad situation because they are a great team. “But I would imagine they are confused with this car. They promise a great result, get something special, then go to the next race with upgrades and fall off the pace.” Mercedes have claimed just one victory in the past 19 months. Their poor form is a far cry from the dominance which saw them secure an unprecedented eight consecutive constructors’ titles. And Russell revealed the Brackley team have been drawing creativity from their once all-conquering machines. “We are working really hard on the characteristics for next yea, and we are looking a lot at how the previous generation of cars were for Mercedes, the glory years, and using that as inspiration,” said Russell. “Clearly they were some of the best cars in history. So that is giving us some pointers of where we need to aim for. “I am sure we will be strong in the second half of the season. We have some little things coming after the break and I am confident we will secure second in the team championship and close the gap to Red Bull.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Max Verstappen taunts F1 rivals with ‘pit-stop training’ offer Max Verstappen beats Oscar Piastri to sprint race pole in Belgium How Max Verstappen and record-breaking Red Bull compare to Formula One greats
2023-07-31 19:15
Sexual assault claims cast light on Australia's macho politics
Sexual assault claims cast light on Australia's macho politics
Australia has allowed a sexist culture to fester inside its parliament, a prominent lawmaker has told AFP, as sexual assault allegations again ring through...
2023-06-19 15:47
The brand new Apple Watch Series 9 is already $10 off at Amazon
The brand new Apple Watch Series 9 is already $10 off at Amazon
SAVE $10: As of September 15, the Apple Watch Series 9 (41mm, GPS) is on
2023-09-15 23:30
Unborn babies use ‘greedy’ father gene to get more nutrients from mothers, study finds
Unborn babies use ‘greedy’ father gene to get more nutrients from mothers, study finds
Unborn babies are in a perpetual nutritional tug-of-war with their mothers due to a “greedy” gene inherited from their fathers, a new study suggests. Scientists from the University of Cambridge have found that foetuses use the gene to “remote-control” their mother into feeding them extra food and control her metabolism. While the mother’s body wants the baby to survive, it needs to keep enough glucose and fats circulating in her system for her own health in order to be able to deliver the child, breastfeed, and reproduce again. Amanda Sferruzzi-Perri, professor in Foetal and Placental Physiology, a Fellow of St John’s College and co-senior author of the paper, said: “It’s the first direct evidence that a gene inherited from the father is signalling to the mother to divert nutrients to the foetus.” Dr Miguel Constancia, MRC investigator based at the Wellcome-MRC Institute of Metabolic Science and co-senior author of the paper, said: “The baby’s remote control system is operated by genes that can be switched on or off depending on whether they are a ‘dad’s’ or ‘mum’s’ gene’, the so-called imprinted genes. “Genes controlled by the father are ‘greedy’ and ‘selfish’ and will tend to manipulate maternal resources for the benefit of the foetuses, so to grow them big and fittest. “Although pregnancy is largely cooperative, there is a big arena for potential conflict between the mother and the baby, with imprinted genes and the placenta thought to play key roles.” The new study looked at how the placenta communicates with the mother through the release of hormones so she can accommodate her baby’s growth. In pregnant mice, scientists selectively altered the signalling cells in the placenta that tell mothers to allocate nutrients to her developing foetuses. The baby’s genes controlled by the father tend to promote foetal growth and those controlled by the mother tend to limit foetal growth, experts say. Professor Sferruzzi-Perri explained: “Those genes from the mother that limit foetal growth are thought to be a mother’s way of ensuring her survival, so she doesn’t have a baby that takes all the nutrients and is too big and challenging to birth. “The mother also has a chance of having subsequent pregnancies potentially with different males in the future to pass on her genes more widely.” In the study researchers deleted the expression of an important gene called Igf2, which provides instructions for making a protein called “Insulin Like Growth Factor Two”. Similar to the hormone insulin, which is responsible for making glucose and controlling its levels in our circulation, the gene promotes foetal growth and plays a key part in the development of tissues including the placenta, liver, and brain. Dr Jorge Lopez-Tello, a lead author of the study based at Cambridge’s department of physiology, development and neuroscience, said: “If the function of Igf2 from the father is switched off in signalling cells, the mother doesn’t make enough amounts of glucose and lipids – fats – available in her circulation. “These nutrients, therefore, reach the foetus in insufficient amounts and the foetus doesn’t grow properly.” The scientists found that deleting the gene also affects production of other hormones that modulate the way the mother’s pancreas produces insulin, and how her liver and other metabolic organs respond. Babies with Igf2 gene defects can be overgrown or growth-stunted. And the researchers say that until now, it was not known that part of the gene’s role is to regulate signalling to the mother to allocate nutrients to the unborn child. The mice studied were smaller at birth and their offspring showed early signs of diabetes and obesity in later life. Professor Sferruzzi-Perri said: “Our research highlights how important the controlled allocation of nutrients to the foetus is for the lifelong health of the offspring, and the direct role the placenta plays. “The placenta is an amazing organ. At the end of pregnancy, the placenta is delivered by the mother, but the memories of how the placenta was functioning leaves a lasting legacy on the way those foetal organs have developed and then how they’re going to function through life.” The findings are published in the Cell Metabolism journal. Reporting by PA Read More It took until my thirties to realise I might not be white Carrie Johnson announces birth of third child with Boris Johnson: ‘Guess which name my husband chose’ How many children does Boris Johnson have? The meaning behind the name of Carrie and Boris Johnson’s third child Emilia Clarke’s brain haemorrhage ‘profoundly changed our lives’, says star’s mother How many children does Boris Johnson have?
2023-07-11 23:21
iOS 17 Siri can read Safari articles for you: 5 other new things it can do
iOS 17 Siri can read Safari articles for you: 5 other new things it can do
iOS 17 officially rolled out to the masses in mid-September, which means iPhone users have
2023-09-27 22:48
'Fionna and Cake' review: 'Adventure Time' spinoff goes so hard it hurts
'Fionna and Cake' review: 'Adventure Time' spinoff goes so hard it hurts
Fionna and Cake feels like a fever dream for Adventure Time lovers. The new spinoff
2023-09-01 17:21
France and EU to spend 215 million euros shoring up struggling wine producers
France and EU to spend 215 million euros shoring up struggling wine producers
The French government and the European Union will spend 200 million euros ($215 million) to help the country's wine producers, who are struggling to cope with falling prices and waning demand.
2023-08-26 19:48
Saudi charges women's activist with spreading 'propaganda'
Saudi charges women's activist with spreading 'propaganda'
Saudi Arabia has charged a women's rights activist detained since November over her social media posts with launching a "propaganda campaign", according to court documents...
2023-06-01 01:58
Mel B reveals fitness secrets for women in 'later years'
Mel B reveals fitness secrets for women in 'later years'
Mel B has urged people to "embrace" body confidence and not be put off by the gym in their later years.
2023-09-22 17:22
Sean 'Diddy' Combs accuses liquor giant Diageo of racism in lawsuit
Sean 'Diddy' Combs accuses liquor giant Diageo of racism in lawsuit
Music producer and rapper Sean "Diddy" Combs is suing spirits company Diageo, accusing it of neglecting their business agreement and failing to invest in his...
2023-06-01 17:19