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How to watch U.S. Prime Video from anywhere in the world
How to watch U.S. Prime Video from anywhere in the world
Prime Video is the seriously popular on-demand streaming service that hosts literally thousands of movies,
2023-07-25 18:16
9 Genderless Fragrances That Are Anything But Boring
9 Genderless Fragrances That Are Anything But Boring
Whether you’re an olfactory fanatic looking for your new signature scent or you’re just starting to dip your toes into the genderless scented pool, we all need a new scent every once in a while — especially for Pride month. But in a world full of colognes and perfumes with harsh gendered lines, it’s hard to figure out which are the truly unisex fragrances. And what exactly do we mean by that?
2023-06-02 04:45
What's streaming now: Doja Cat, 'Sex Education,' 'Spy Kids,' 'The Super Models' and 'Superpower'
What's streaming now: Doja Cat, 'Sex Education,' 'Spy Kids,' 'The Super Models' and 'Superpower'
This week’s new entertainment releases include an album from Doja Cat, a reboot of Robert Rodriguez’s “Spy Kids” franchise with a film starring Gina Rodriguez and Zachary Levi and the critically-acclaimed “Sex Education,” one of Netflix’s most popular shows, returns for its fourth and final season
2023-09-23 04:17
Get 1TB of lifetime cloud storage for $120
Get 1TB of lifetime cloud storage for $120
TL;DR: As of July 30, you can get a Koofr Cloud Storage 1TB Lifetime Subscription
2023-07-30 17:58
In Utah and Kansas, state courts flex power over new laws regulating abortion post-Roe
In Utah and Kansas, state courts flex power over new laws regulating abortion post-Roe
State courts in Utah and Kansas are planning to hear arguments Tuesday in legal challenges involving new abortion laws since the overturning of Roe v. Wade
2023-08-08 13:24
Study reveals how muscle cells deteriorate with age, hampering injury recovery
Study reveals how muscle cells deteriorate with age, hampering injury recovery
Researchers have revealed how muscle cells deteriorate with age, affecting their ability to regenerate and recover after an injury. The findings could help to shed light on why it takes people longer to recover from muscle damage as they age. A team at Nottingham Trent University analysed the genes inside muscle cells, and found the ‘development pathways’ – the different ways in which genes work together to regenerate muscle – become weakened in older cells. We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get Dr Livia Santos, Nottingham Trent University Lead researcher Dr Livia Santos, an expert in musculoskeletal biology in Nottingham Trent University’s School of Science and Technology, said: “This goes some way towards explaining why muscle injuries may take longer to recover as we get older.” She added: “We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get. “What we’ve observed, in terms of what happens inside the cells, helps us to better understand why we don’t heal as well or as quickly in older age. “The pathways that control cell processes and development work differently in older cells and are downregulated, meaning regeneration is impacted the older we get. “If we can understand these pathways, however, we could potentially identify new therapies and interventions to mitigate the problem.” The researchers developed a new approach to examine muscle cells in the laboratory to enable them to observe the different mechanisms that drive muscle ageing. They studied muscle cells from donors, chemically injuring cells after they had been donated and isolated, then assessing how they heal and regenerate back to their pre-injury baseline levels. When they looked at cells from a 20-year-old and a 68-year-old donor, researchers found distinct differences in the development pathways of the younger and older cells. While younger muscle cells fully recovered from the injury, the team found that in older cells the genes expressed less of what they needed to, leaving the cells no longer able to perform in the way they should. According to the researchers, this contributes to reduced regeneration capacity leading to thinner, less robust ‘myotubes’ – a type of cell that can fully develop into a muscle fibre. Muscle regeneration is a complex and finely balanced biological process and is known to deteriorate with ageing, leading to the decline of musculoskeletal health and in some cases metabolic and genetic diseases. Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing Researcher Janelle Tarum Janelle Tarum, another researcher on the study, said: “We’ve been able to develop a new approach to assess muscle regeneration which involves a state-of-the-art technique called RNA-sequencing. “There’s a very clear reduced regeneration capacity and weakened recovery of aged cells and we have been able to further understand the factors underlying this impairment. “Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing.” The study, which also involved Manchester Metropolitan University and Liverpool John Moores University, is published in the Journal of Tissue Engineering and Regenerative Medicine.
2023-08-07 17:59
Charles Leclerc leads Ferrari front row at Mexican Grand Prix
Charles Leclerc leads Ferrari front row at Mexican Grand Prix
Charles Leclerc saw off team-mate Carlos Sainz by just 0.067 seconds as Ferrari locked out the front row for Sunday’s Mexican Grand Prix. Max Verstappen improved on his final run at the Autodromo Hermanos Rodriguez but could not usurp the Ferrari drivers, finishing 0.097 sec adrift. The triple world champion also faces a nervous wait to see if he is moved down the grid after being summoned to see the stewards. Verstappen, charged with impeding on the pit exit, is among four drivers who will be hauled in front of the race officials. Lewis Hamilton, disqualified from finishing runner-up to Verstappen at the United States Grand Prix a week ago, may too feel the wrath of the race referees for failing to slow under yellow flags. Hamilton finished only sixth, 0.288 sec back. George Russell, who qualified eighth, and Fernando Alonso, 13th on the grid, have also been called to see the stewards for blocking on the pit exit in Q1. Verstappen hit the kerb at Turn 8 in his first attempt in Q3 to leaving him trailing Leclerc by 0.120 sec. The Red Bull man, who has won 15 of the 18 rounds so far, produced a better last lap, but could not prevent Leclerc from sealing his second pole in as many weekends. “I didn’t expect to be one pole because we looked to be lacking quite a bit of pace after practice,” said Leclerc. “But for some reason once we put everything together it went well and on the new tyres we gained a lot. “I’m already focusing on tomorrow’s race because we have had many pole positions this season, but we need to convert it into victory and that is going to be very difficult.” Nearly 400,000 spectators will pass through the gates at the high-altitude Mexico City venue this weekend with the majority here to support Sergio Perez. But the home favourite failed to deliver, finishing nearly three tenths adrift of Verstappen and qualified fifth, one position behind Daniel Ricciardo who impressed in his AlphaTauri. Earlier, Lando Norris was the surprise name eliminated from the opening phase of qualifying, leaving the in-form British driver in 19th place. Norris, who has finished on the podium at the past four races, attempted to progress from Q1 on the slower medium rubber in order to save a set of speedier softs. But the plan backfired when Norris’ lap wasn’t quick enough. Norris bolted on the soft tyres but then made a mistake a Turn 10. He aborted the lap and prepared for one last attempt, only to run into yellow flags at the opening bend after Alonso spun in his Aston Martin. Norris’ qualifying was over leaving him a tall order to salvage anything from tomorrow’s race. American rookie Logan Sargeant, who earned his first point in F1 last weekend in Austin, will prop up the grid after he saw two laps scrubbed off by the stewards for exceeding track limits. Read More Essex boy with Italian twang – History-maker Ollie Bearman impresses in Mexico Max Verstappen sets fastest time in Mexican Grand Prix practice Max Verstappen urges fans to show him respect ahead of feisty Mexican Grand Prix Lewis Hamilton claims many more cars were illegal at United States Grand Prix Max Verstappen beefs up security in preparation for hostile reception in Mexico On this day in 2015: Lewis Hamilton crowned F1 world champion for third time
2023-10-29 06:48
The black bit at the end of a banana is not as gross as you might think
The black bit at the end of a banana is not as gross as you might think
When you chow down on a banana, you might often see a black bit at the end and it looks a bit gross. But what is it? Some people think it is the seed, but these are found down the middle, if at all, as the Cavendish variety of bananas, which is commonly sold typically doesn’t produce any seeds. It is actually something completely different. Bananas are technically berries and the black bit is the nub of the flower from which the giant banana berry grew. Bananas grow on trees in bunches, and the end is actually the top of the fruit while the hard stalk is the bottom. But given most people eat bananas by snapping off the stalk first, the residual flower nub is left at the end. This black bit is entirely edible but people often throw it away because it has a tough texture and a bitter taste. So now you know, there is nothing stopping you from getting one of your five a day. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.
2023-09-14 20:24
Whisky lifts spirits of inflation-hit investors
Whisky lifts spirits of inflation-hit investors
The smell of ageing whisky, known as the angel's share, wafts across from 9,000 oak barrels stored from floor to ceiling in two vast...
2023-05-31 10:46
‘I was passing out in the car’ says Lance Stroll as Qatar heat takes its toll
‘I was passing out in the car’ says Lance Stroll as Qatar heat takes its toll
Lance Stroll claimed he passed out at the wheel of his Aston Martin because of the extreme humidity in Sunday’s Qatar Grand Prix. American rookie Logan Sargeant was forced to retire through illness, French driver Esteban Ocon said he vomited in his cockpit, while London-born Thai Alex Albon was taken to the medical centre with acute heat exposure as the grid’s drivers battled the intense conditions at the Lusail International Circuit. A statement from 27-year-old Albon’s Williams team read: “Following the Qatar Grand Prix, Alex was taken to the medical centre to be treated for acute heat exposure. He has now been assessed and cleared by the medical team.” Williams also revealed Sargeant, 22, had suffered from “intense dehydration” following “flu-like symptoms earlier in the week”. Aston Martin’s Stroll, 24, who fell over as he made his way to conduct his media duties, said: “I was passing out in the car. “They painted the kerbs and made the track narrower but you can’t feel the kerbs. I couldn’t see where I was going because I was passing out. I was fading in and out. The temperature was too much.” George Russell, who finished fourth following a first-lap collision with Mercedes team-mate Lewis Hamilton, also revealed he felt ill throughout Sunday’s 57-lap Grand Prix. I was passing out in the car Lance Stroll The 25-year-old said: “It was an absolutely brutal race and by far the most physical race I have ever experienced. “I felt close to fainting in that race and I have never experienced anything like it before. “I wasn’t physically sick in the car but I felt ill. I had to ask my engineer to give me encouragement to take my mind off of it.” This was only the second staging of the Qatar race and the first of a 10-year deal. Next year’s edition will be held two months later in December when it is expected to be cooler. Read More Lewis Hamilton and George Russell vent anger on radio after collision in Qatar Lewis Hamilton crashes out after first-corner collision with George Russell In his own words: Christian Horner on world champion Max Verstappen Angry Lance Stroll shoves personal trainer and storms out of interview Max Verstappen fastest in Qatar practice as he closes in on world championship Fernando Alonso lauds Max Verstappen as best F1 driver since Michael Schumacher
2023-10-09 04:50
NYT Connections today: See hints and answers for November 7
NYT Connections today: See hints and answers for November 7
Connections is the latest New York Times word game that's captured the public's attention. The
2023-11-07 18:19
Sarah Beeny shares health update after all-clear from breast cancer
Sarah Beeny shares health update after all-clear from breast cancer
Sarah Beeny has said she is feeling happy and well after being given the all-clear from cancer by her doctors. The TV presenter and property expert, 51, was diagnosed with breast cancer in August last year. In April she was told she was all-clear from the disease. In recent months, Beeny has been working on a new Channel 4 documentary that follows her journey from diagnosis to treatment. Appearing on BBC‘s The One Show on Monday (29 May), the presenter said she “always feared” getting breast cancer after her mother died from the same cancer when Beeny was 10 years old. “When I got to 39, which is the age she died, I thought ‘Here we are.’ And then I got to 40 and thought, that’s weird!” she said. “And then I got to 50 and got the diagnosis.” “I’ve lived with this fear for such a long time,” she continued. “But once I realised how the treatment works, it’s not nearly as bad as the fear.” Appearing on Lorraine in April, Beeny said her cancer journey had been a “rollercoaster ride”. ​​“But I feel very fortunate that I had the diagnosis that I did, and that I live in 2023 and that I’m the age that I am. So many things I’m fortunate for, so I feel very blessed,” she said. Beeny, who received chemotherapy, said she would have to take medication for the next 10 years and remain “very vigilant”. “But, yeah, it’s been a weird ride that I wouldn’t wish on anyone else but I’m glad I did it rather than somebody else,” she added. Beeny has four children: Rafferty, Laurie, Billy and Charlie; and married her husband, artist Graham Swift, in 2003. Her family appears in her Channel 4 series Sarah Beeny’s New Life In The Country, which was filmed before her diagnosis. Sarah Beeny: Breast Cancer, My Family and Me will air on Monday 12 June on Channel 4 at 9pm. Read More College student goes viral after sharing her wild two hour commute everyday: ‘This is a journey’ Mother’s warning after viral TikTok hack left skin peeling from her face The ideal age gap for a relationship if you want it to last, according to experts Sarah Beeny shares health update after all-clear from breast cancer Breast cancer symptoms and survival rate as Amy Dowden diagnosed Signs and symptoms of breast cancer as Amy Dowden reveals diagnosis
2023-05-31 20:25