2023 has been a pretty miserable year for superhero movies, bringing us the underwhelming Shazam!

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So you’ve been counting down to your holiday – when you’ll finally have the chance to step off the hamster wheel and relax. Except, no sooner have you checked in at your hotel than you find yourself reaching for the headache pills or tissues, as a niggling cold or migraine takes hold. Sound familiar? If it feels like you suddenly get unwell when you finally hit the pause button, you’re not imagining it – there’s even a medical term for it. The ‘let-down effect’ “This is known as the ‘let-down effect’,” says Dr Suhail Hussain, a personal physician and private home visiting GP. “When the body is used to functioning on high levels of [stress hormones] cortisol and adrenaline and they suddenly decrease, our immune system is exposed and then we’re prone to minor infections and excessive tiredness. “Pain and muscle aches also increase – adrenaline increases muscle tension, so imagine a rubber band always pulled tight, what happens when you let go? “There may also be a spike in mental health problems, such as acute anxiety and panic attacks. Flare-ups in pre-existing chronic conditions is also a common phenomenon, for example migraine and asthma attacks,” he adds. The ‘let-down effect’ can strike after a brief period of intense stress, such as after exams or completing a project, and after positive high-stress events, like planning a wedding. And for many people, it hits when you finally get to put down your to-do list and go on holiday. What’s the deal with stress hormones? Stress hormones serve an important purpose and we need them to function, so they’re not always bad news. “Basically, we are programmed to respond to danger – ‘fight or flight’ – so in stressful situations, there is an increase in levels of stress hormones adrenaline and cortisol,” Dr Hussain explains. “Together, these two hormones control mood, motivation and fear. In periods of stress or heightened anxiety, adrenaline levels rise – causing an overdrive of the sympathetic nervous system, resulting in racing pulse, high blood pressure, sweating, etc.” Stress hormones also play a role in regulating inflammation, metabolising nutrients, and aiding immune function, sleep and energy. But ideally, they wouldn’t stay at raised levels for too long. “If these hormones are always ‘on’, then inflammatory processes are accelerated and your immune system is impaired,” says Dr Hussain. “Consistently high levels of cortisol in your blood can lead to inflammation and a weakened immune system.” Can you avoid the ‘let-down effect’? Dr Hussain says: “You can try to lessen the impact of the ‘let-down effect’ by de-stressing slowly. Instead of crashing and burning, try to maintain a bit of activity on the holiday or some degree of exercise, such that there’s not a massive decrease in stress hormone levels, meaning you can allow the body to acclimatise slowly.” But not getting sick on holiday may not be the only concern here. If your body is giving you warning signs that chronic stress is taking a toll, it’s important to listen. “Constantly running on high levels of stress is very bad for you. It leads to the problems mentioned above but also longer-term consequences, such as plaque formation in arteries, leading to coronary events and strokes, depression and anxiety, and even addiction. Levels of obesity are also increased,” explains Dr Hussain. He says indications to look out for could include: “Recurrent illnesses, feeling tired, lack of energy. Poor response to glucose, leading to type 2 diabetes, elevated blood pressure and disruption of the sleep-wake cycle.” If you have any concerns, check in with your GP. And Dr Hussain suggests finding ways to make managing stress in everyday life. “Build in regular relaxation to your daily schedule. Get out to walk, spend time in the sun, observe nature. Listen to relaxing music. Make a regular sleep schedule, read, spend time with family and loved ones,” he says. “Don’t just work and work and work for the expectation of a big holiday at the end of it.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live As Katie Boulter takes Wimbledon by storm, we look at her best on-court fashion so far Lioness Katie Zelem: Nerves are good – it’s just about channelling them the right way Church of England should scrap fees of up to £641 for weddings, vicar says

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LOS ANGELES--(BUSINESS WIRE)--Sep 20, 2023--

The prolonged shortage of a certain red sauce is making the black market go wild.

Lando Norris denied Max Verstappen a practice double by setting the pace for Sunday’s Dutch Grand Prix – after Daniel Ricciardo crashed out and was taken to hospital. More than 300,000 spectators will descend on the coastal town of Zandvoort, 30 miles outside of Amsterdam, as Formula One emerges from its summer slumber. The majority of whom will do so in the expectation of watching Verstappen march to his ninth consecutive victory – equalling a record set by Sebastian Vettel for Red Bull in 2013 – as he closes in on a hat-trick of world championships. But McLaren’s Norris raised the suggestion he could spoil Verstappen’s homecoming party after he ended the day with the fastest time. While practice speed is treated with caution, the British driver edged out Verstappen, who was fastest in the first running, by just 0.023 seconds. The impressive Alex Albon finished third for Williams, one place ahead of Mercedes’ Lewis Hamilton. The seven-time world champion finished three tenths adrift in his Mercedes with team-mate George Russell only 14th in the order. The second session was suspended after just 10 minutes when Norris’ team-mate Oscar Piastri and AlphaTauri’s Ricciardo crashed out at the same corner. Australian Piastri, who has enjoyed an impressive rookie campaign, lost control of his McLaren through the banked left-handed Turn 3 before slamming into the barriers. Moments later, Ricciardo, who appeared distracted by the sight of Piastri’s wounded McLaren, locked up under braking before following his compatriot into the tyre wall. “Ah f***, my hand, f***,” the 34-year-old said over the radio after the incident. Both men played no further part in the running as their damaged cars were towed back to their respective garages. Ricciardo was still holding the steering wheel as he hit the wall, and he was taken to the medical centre. He was then pictured leaving with his left arm in a sling, and was subsequently taken to a nearby hospital for further checks on his wrist, raising some doubt over his participation for the remainder of the weekend. Ferrari have endured a lacklustre campaign and there was little for the Italian giants to cheer on Friday, with Charles Leclerc 11th and team-mate Carlos Sainz 16th. Ricciardo’s team-mate, Yuki Tsunoda, finished fifth with Pierre Gasly sixth and Sergio Perez, 125 points behind Verstappen in the drivers’ championship, seventh. Read More F1 returns with the now inevitable question: can anyone beat Max Verstappen? Lewis Hamilton gives blunt response to Felipe Massa’s legal action over 2008 F1 title F1 2023 race schedule: When is the Dutch Grand Prix? F1 Dutch Grand Prix LIVE: Practice updates and times as Formula 1 returns F1 returns with the now inevitable question: can anyone beat Max Verstappen?

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