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So you’ve been counting down to your holiday – when you’ll finally have the chance to step off the hamster wheel and relax. Except, no sooner have you checked in at your hotel than you find yourself reaching for the headache pills or tissues, as a niggling cold or migraine takes hold. Sound familiar? If it feels like you suddenly get unwell when you finally hit the pause button, you’re not imagining it – there’s even a medical term for it. The ‘let-down effect’ “This is known as the ‘let-down effect’,” says Dr Suhail Hussain, a personal physician and private home visiting GP. “When the body is used to functioning on high levels of [stress hormones] cortisol and adrenaline and they suddenly decrease, our immune system is exposed and then we’re prone to minor infections and excessive tiredness. “Pain and muscle aches also increase – adrenaline increases muscle tension, so imagine a rubber band always pulled tight, what happens when you let go? “There may also be a spike in mental health problems, such as acute anxiety and panic attacks. Flare-ups in pre-existing chronic conditions is also a common phenomenon, for example migraine and asthma attacks,” he adds. The ‘let-down effect’ can strike after a brief period of intense stress, such as after exams or completing a project, and after positive high-stress events, like planning a wedding. And for many people, it hits when you finally get to put down your to-do list and go on holiday. What’s the deal with stress hormones? Stress hormones serve an important purpose and we need them to function, so they’re not always bad news. “Basically, we are programmed to respond to danger – ‘fight or flight’ – so in stressful situations, there is an increase in levels of stress hormones adrenaline and cortisol,” Dr Hussain explains. “Together, these two hormones control mood, motivation and fear. In periods of stress or heightened anxiety, adrenaline levels rise – causing an overdrive of the sympathetic nervous system, resulting in racing pulse, high blood pressure, sweating, etc.” Stress hormones also play a role in regulating inflammation, metabolising nutrients, and aiding immune function, sleep and energy. But ideally, they wouldn’t stay at raised levels for too long. “If these hormones are always ‘on’, then inflammatory processes are accelerated and your immune system is impaired,” says Dr Hussain. “Consistently high levels of cortisol in your blood can lead to inflammation and a weakened immune system.” Can you avoid the ‘let-down effect’? Dr Hussain says: “You can try to lessen the impact of the ‘let-down effect’ by de-stressing slowly. Instead of crashing and burning, try to maintain a bit of activity on the holiday or some degree of exercise, such that there’s not a massive decrease in stress hormone levels, meaning you can allow the body to acclimatise slowly.” But not getting sick on holiday may not be the only concern here. If your body is giving you warning signs that chronic stress is taking a toll, it’s important to listen. “Constantly running on high levels of stress is very bad for you. It leads to the problems mentioned above but also longer-term consequences, such as plaque formation in arteries, leading to coronary events and strokes, depression and anxiety, and even addiction. Levels of obesity are also increased,” explains Dr Hussain. He says indications to look out for could include: “Recurrent illnesses, feeling tired, lack of energy. Poor response to glucose, leading to type 2 diabetes, elevated blood pressure and disruption of the sleep-wake cycle.” If you have any concerns, check in with your GP. And Dr Hussain suggests finding ways to make managing stress in everyday life. “Build in regular relaxation to your daily schedule. Get out to walk, spend time in the sun, observe nature. Listen to relaxing music. Make a regular sleep schedule, read, spend time with family and loved ones,” he says. “Don’t just work and work and work for the expectation of a big holiday at the end of it.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live As Katie Boulter takes Wimbledon by storm, we look at her best on-court fashion so far Lioness Katie Zelem: Nerves are good – it’s just about channelling them the right way Church of England should scrap fees of up to £641 for weddings, vicar says

The Eurovision Song Contest is almost upon us, and the week-long competition will be held in Liverpool. Home to the Beatles and Cilla Black, the Scouse city has a rich musical history. Music and fashion often go hand in hand – and Eurovision will certainly deliver this. Onstage we’ll likely see all manner of sartorial statements, ranging from the glamorous to the slightly ridiculous. Perhaps contestants will take inspiration from some of Liverpool’s most fashionable musical icons for their costumes… The Beatles No list of Scouse musicians would be complete without The Beatles. The band’s music was influential beyond compare, and John Lennon, Paul McCartney, George Harrison and Ringo Starr were trendsetters in their own right. Each era of their music had a dedicated aesthetic – from the sharp suits of the early Sixties, to the psychedelic fashion of Sgt. Pepper’s Lonely Hearts Club Band. Cilla Black With her cropped red hair and dedication to Mod-style mini dresses, Cilla Black – who burst onto the scene with songs Anyone Who Had A Heart and You’re My World – was a Sixties trendsetter. She was unafraid to buck convention – such as wearing a red velvet minidress to marry in 1969. While less of a trendsetter in the decades that followed, Black remained stylish – wearing gowns on the red carpet, showing a commitment to sharp tailoring – and donning a shirt and tailcoat with no trousers on the runway in 2008. Elvis Costello Part of being a fashion icon is having a defining look, and that’s something Elvis Costello has honed to perfection. The Watching The Detectives singer wasn’t born in Liverpool, but has been claimed by the city after living there for a few years as a teenager. Costello is known to be a keen supporter of Liverpool FC. Costello first debuted his signature look of oversized glasses on the cover of his debut album – 1977’s My Aim Is True – and that has continued throughout his career, often paired with a fedora. Mel C As Sporty Spice, Melanie Chisholm – better known as Mel C – wasn’t originally seen as the fashionable one of the girl group. However, her commitment to sportswear was particularly prescient, long before the athleisurewear trend hit the mainstream. Nowadays, Chisholm is bang on trend by combining sportswear into her everyday outfits, while mixing things up with more grown-up accents of tailoring and more glam looks. Atomic Kitten With low-rise trousers, crop tops, butterfly motifs and blue sunglasses, Atomic Kitten’s fashion was the epitome of Noughties fashion – regardless of what combination of Kerry Katona, Liz McClarnon, Jenny Frost and Natasha Hamilton were in the line-up. The band’s fashion ticked almost every 2000s style box you can imagine – with chunky highlights in their hair, cargo pants, mini skirts, trailing scarf belts, flat caps, corset tops and more. And with the resurgence of Y2K fashion, you can now see trends Atomic Kitten championed all over Instagram and TikTok. Rebecca Ferguson Propelled to fame on the 2010 series of The X Factor, Liverpudlian soul singer Rebecca Ferguson will play a role in this year’s Eurovision. She will perform alongside Rita Ora in the semi-final at Liverpool ACC. In terms of fashion, Ferguson is a lover of extremely glamorous gowns – often with sparkles and standout detailing like capes. Her love of dramatic gowns was shown last year when she got married to Jonny Hughes in a sparkly, princess-style gown complete with a tiara and long veil. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live 14 clever ways to make small rooms look bigger What’s in store at this year’s RHS Chelsea Flower Show? Woman in ‘living hell’ with brain slipping down her spine after ice-skating accident

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