In many ways, San Francisco's downtown is in dire straits. The city's once bustling Union Square neighborhood, once teeming with shoppers, diners, and tourists, has suffered declining foot traffic and closing stores.

Stores, restaurants and independent entrepreneurs are taking full advantage of the history-making success of the "Barbie" movie to merchandise all kinds of pink products.

A summit between Russian President Vladimir Putin and African leaders began in St. Petersburg on Thursday, with a far lower turnout than previous years.

Bad news for boozers - alcohol is linked to more than 60 diseases. According to new Oxford University research published Thursday in the journal Nature Medicine, even occasional drinkers were at a higher risk for certain conditions, including more than 30 illnesses not previously linked to alcohol. The researchers studied the effects of alcohol on 512,000 men and women in China for 12 years. 41 per cent of those studied were man and they were all recruited from 10 areas across China and drank at different frequencies. “Alcohol consumption is adversely related to a much wider range of diseases than has previously been established, and our findings show these associations are likely to be causal,” lead study author Pek Kei Im, a research fellow at Oxford Population Health, said in a statement. Sign up to our free Indy100 weekly newsletter 28 ailments the researches found had already been tied to drinking, such as esophageal cancer, liver disease and diabetes. The remaining 33 had not been established as drinking-related illnesses, including stomach and lung cancers, gastric ulcers and gout. “It is becoming clear that the harmful use of alcohol is one of the most important risk factors for poor health, both in China and globally,” said senior study author Iona Millwood, an associate professor at Oxford Population Health. Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

The Supreme Court on Thursday sided with Jack Daniel's in a dispute over a poop-themed dog toy that parodies its iconic liquor bottle.

Mark your calendars: Smartphone vendor Nothing plans on holding a launch event for its second-generation

TL;DR: As of October 30, you can get a refurbished Dell 11.6-inch 2-in-1 Chromebook for

Using ChatGPT can result in a mixed bag of helpful information and nonsensical answers, making

A man accused of impregnating an Ohio child -- a girl who then went to Indiana for an abortion in a case that became a flashpoint in debates about post-Roe v. Wade abortion rights -- was sentenced to life in prison Wednesday after pleading guilty to rape, according to court documents.

Thousands of families in the West Bank and Gaza Strip are struggling with deep food insecurity two months after being cut from the United Nations’ main food assistance program

Girlfriend Collective’s sustainable workout togs were built for movement. The brand’s cloud-like leggings, stylishly cut sports bras, and super-soft separates are serious momentum-builders. The line is so action-packed, in fact, that customers are getting a head start in their sprint toward the shopping finish line with the launch of its anniversary sale. Starting today, customers can score 25% off everything on the Girlfriend Collective site and up to 50% off select on-sale styles. This includes reader-adored (and Shopping-team vetted) leggings, bike shorts, bras, and exercise dresses — all made with earth-friendly materials like recycled polyester and organic cotton. The discount will be applied at checkout, so you don’t have to do a thing except fill your cart. (Save your energy for when your workout wardrobe arrives in the mail.)

Maybe you want to create an app to share photos with other dog owners at