VIENNA, Va.--(BUSINESS WIRE)--Aug 17, 2023--

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Bats could hold the key to unlocking new ways to combat cancer, a new study suggests. A paper published by Oxford University Press, looks at the rapid evolution of bats for their abilities to both host and survive infections such as Covid-19 as well as cancer. The animals are known to have a strong immune system which helps fight off many viruses and diseases. These mammals are also thought to have played a role in the emergence of Covid-19 and scientists say such characteristics are interesting to investigate due to the implications it might have on human health. According to the research, understanding the mechanisms of the bat’s immune system that allows these animals to fight off viral infections – may pave the way to understanding how to prevent disease outbreaks from animals to people. To conduct the study, researchers sequenced the genomes of two bat species - the Jamaican fruit bat and the Mesoamerican mustached bat. The team used advanced technology from Oxford Nanopore Technologies and bat samples collected by the American Museum of Natural History in Belize. They then compared the bat genomes to those of other mammals. The results revealed that bats possessed genetic adaptations in proteins which are related to DNA repair and cancer suppression. It was found that bats had adaptations in six DNA repair-related proteins and 46 cancer-related proteins. The study also found that bats had more than double the number of altered cancer-related genes compared to other mammals, which provided further evidence that they have the ability to suppress cancer. “By generating these new bat genomes and comparing them to other mammals we continue to find extraordinary new adaptations in antiviral and anticancer genes,” said the paper’s lead author, Armin Scheben. “These investigations are the first step towards translating research on the unique biology of bats into insights relevant to understanding and treating ageing and diseases, such as cancer, in humans.” The results open up new paths for understanding and studying the links between cancer and immunity, which offers hope that these insights from bats might possibly lead to new treatments for human illnesses. According to the United States Department of the Interior, there are over 1,400 species of bats worldwide and are mostly found in extreme deserts and polar regions. In the US and Canada, there are about 45 species of bats. Read More British bats ‘can help identify coronaviruses with potential to infect humans’ Coronavirus origins still a mystery 3 years into pandemic Groundbreaking migraine treatment offers ‘new hope’ for patients World Sepsis Day: What is the condition and its symptoms? Duran Duran’s Andy Taylor says he’s ‘asymptomatic’ after end-of-life diagnosis

Max Verstappen has hit back at criticism of his dominance and set the target of remaining unbeaten for the final nine races of the season. The all-conquering Dutchman will become the first driver in history to win 10 consecutive races if he takes the chequered flag at the Italian Grand Prix on Sunday. Verstappen has been in imperious form this year, winning 11 of the 13 rounds staged as he closes in on a hat-trick of World Championships. With a lead of 183 points heading into this weekend’s race in Monza there is a chance he could even close out the title with six rounds still remaining at the Japanese Grand Prix on September 24. However, Verstappen’s emphatic streak has led to suggestions that the sport has become boring. But responding to the accusations in an interview with the PA news agency, Verstappen, 25, said: “They cannot appreciate dominance or just people executing their jobs. “It is nothing really new in Formula One, and I cannot do much with those kind of comments. Does it bother me? No. It would probably be worse if they were talking about other stuff. I am enjoying what I am doing and I hope I can do it for a while. “I don’t want it to stop. We have another good opportunity this weekend. I believe I can win every single race.” Verstappen’s victory on his home track in Zandvoort – which drew him level with Sebastian Vettel’s record of nine straight wins – was among the very best of the 46 of his career so far. At one stage, he was lapping four seconds faster than Sergio Perez in the other Red Bull, and two seconds quicker than anybody else. His virtuoso display in the inclement conditions prompted double world champion Fernando Alonso to say Verstappen’s achievements are being underestimated. “It is not about getting the recognition because I know how hard it is to do,” said Verstappen. “If it was very easy, more drivers would have won nine in a row, and more teams would have done it, and that is not the case. “It hasn’t been straightforward either. In Zandvoort especially, a lot of things could have gone wrong, and in the end we still handled that really well. “I never thought I would get to nine. I remember watching Seb do it, and I was like, ‘Jesus Christ, that is extremely difficult’, and now I am here and it is amazing.” Verstappen will share the grid with long-time rival Lewis Hamilton for at least another two seasons after the British driver signed a new £50million-a-year deal to remain with Mercedes. The contract extension will take Hamilton beyond his 40th birthday, and provides the possibility of a championship rematch with Verstappen if Mercedes can somehow close the gap to Red Bull. Hamilton, who was denied an eighth world title after race director Michael Masi failed to follow the correct rules in Abu Dhabi in 2021, alluded to “unfinished business” after signing his latest deal. Twenty months on from F1’s most contentious race, does Verstappen – who, on new tyres, had to pass Hamilton on the final lap to take the title – feel his maiden championship triumph was tainted? “It was not like it was given to me,” he said. “I still had to do it. “People always have short memories and they can forget a lot of stuff very quickly. “It was a great year, and we had a lot of great battles with two teams going at it and that was amazing for Formula One. “But you will always have a winner, and you will always have a loser. That is how this sport works, and I was also ready to lose. “It was a 50-50 chance and it fell my way. But in the future I could be in a situation where it doesn’t fall my way and that is how life goes. “I don’t really care a lot about other people’s opinions. I only care about people that are very close to me so whatever people say or write, I am like ‘whatever’. “I grew up my whole life wanting to be a Formula One driver and I will do everything it takes to try and be successful at it. “I make my choices and my decisions and that is why I am very relaxed about these things. I go home, I switch off from Formula One, and I am happy with my career. And when I come back to the race weekends I do my thing, and that is it.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live How Max Verstappen equalled Sebastien Vettel’s record for consecutive race wins Max Verstappen reveals Sebastian Vettel prediction as he closes on GP record run Max Verstappen is one of the best drivers in F1 history – Lando Norris

Max Verstappen has beefed up his personal security as he prepares for a hostile reception at Red Bull team-mate Sergio Perez’s home race in Mexico. Verstappen was jeered by Perez’s supporters at last weekend’s podium presentation in Austin as the triple world champion celebrated his 15th win of the season. Chants of “Checo, Checo” – in support of Perez – were also audible during the Dutch national anthem. A crowd of nearly 400,000 are expected at the high-altitude Autodromo Hermanos Rodriguez over the course of the weekend, with practice starting on Friday and it is understood Verstappen will be flanked by multiple security guards in the paddock. Perez’s fans are unhappy Verstappen did not help the Mexican secure second place in last season’s championship after he ignored a team order at the penultimate round in Brazil. Perez has won only twice this season – his last victory in Azerbaijan on April 30 – with Verstappen racing to his third title in as many years. The paddock in Mexico City has become one of the most manic on the calendar, with drivers mobbed as they make their way from the motorhome to the garage. And Perez is also expected to have a bigger entourage than normal to cover-off his enthusiastic fanbase. Red Bull team principal Christian Horner and the team’s motorsport advisor Dr Helmut Marko will also be accompanied by security guards. Speaking after last weekend’s race in Austin, Horner said: “I don’t think Max is going to get the warmest reception in Mexico, but that is water off a duck’s back to him. “One year you are the villain and the next year you are the hero.” Perez heads into this weekend’s round 206 points behind Verstappen. However, he is 39 points clear of third-placed Lewis Hamilton, who was disqualified from second at the Circuit of the Americas for running an illegal floor on his Mercedes.