Scientists make surprising discovery that could help boost the global population
Infertility is a problem that afflicts more than a billion people across the world, which is why treatments such as IVF are so important. The procedure (in vitro fertilisation, to use it’s full name) involves the extraction of an egg from the woman's ovaries to be fertilised with sperm in a laboratory and returned to the woman’s womb. The goal is that the resulting embryo will then grow and develop into a foetus, blessing the parent or parents with a baby. However, success rates for IVF – as in, the percentage of treatments that result in a live birth – remain somewhat unencouraging: 32 per cent for women aged under 35; 25 per cent for women aged 35 to 37, with the numbers continuing to drop the older you get, according to the NHS. Nevertheless, a major new study has revealed a striking new finding which could help boost the hopes of countless aspiring mums and dads across the world. Sign up for our free Indy100 weekly newsletter After analysing 3,657 frozen embryos over a period of eight years, researchers in Western Australia found that IVF was much more likely to work when eggs had been harvested in the summer. The team clarified that it didn’t seem to matter when the embryos were transferred to the mother’s womb, just when the eggs were collected. Indeed, the likelihood of babies being born when the eggs had been retrieved in the summer was 30 per cent higher than when they had been retrieved in the autumn, according to the scientists. The team also found that the temperature on the day of egg collection didn’t seem to have an impact on success rates, but the number of sunny hours did. Of the embryos they tested, those harvested on days that had the most sunshine were 28 per cent more likely to result in a live birth compared to the darkest and most overcast days. “Our study suggests that the best conditions for live births appear to be associated with summer and increased sunshine hours on the day of egg retrieval,” the study’s lead, Dr Sebastian Leathersich, of Perth’s King Edward Memorial Hospital, said about the paper, which was published in the journal Human Reproduction. Still, he noted: “There are many factors that influence fertility treatment success, age being among the most important. “However, this study adds further weight to the importance of environmental factors and their influence on egg quality and embryonic development." He further explained: “We effectively separated the conditions at the time of egg collection from the conditions at the time of transfer, demonstrating that environmental factors when the eggs are developing are as, if not more, important than environmental factors during implantation and early pregnancy.” The expert obstetrician and gynaecologist added: “Optimising factors such as avoiding smoking, alcohol and other toxins and maintaining healthy activity levels and weight should be paramount. However, clinicians and patients could also consider external factors such as environmental conditions.” Despite Dr Leathersich and his colleagues concluding that the temperature on the day of egg collection had little bearing on the success of the process, they also found that the temperature on the day of embryo implantation did make a difference. The chances of a live birth rate decreased by 18 per cent when the embryos were transferred on the hottest days (when average temperatures measured between 14.5C and 27.8C) compared to the coolest days (0.1C to 9.8C), and there was a small increase in miscarriage rates, from 5.5 per cent to 7.6. The finding that miscarriage rates were highest when embryo transfer took place on the hottest days is consistent with other studies showing higher rates of miscarriage in the summer months. “This suggests that the negative effects of high temperature are more likely related to early pregnancy rather than egg development,” Dr Leathersich concluded. When it comes to the disparity in success rates between eggs retrieved in summer and autumn, he and his team pointed out that melatonin levels could be at play. Differences in lifestyles between the winter and summer months may also play a role, he and his colleagues acknowledged. "It is possible that there are differences in activity, diet, and lifestyle in different seasons which could underlie the observed differences in live birth rates, though such data were not collected in this study," they wrote. "It is also possible that other environmental factors, including pollutants, may impact clinical outcomes." Whilst the study’s findings are compelling, Dr Leathersich and his team admitted that it did have its limitations. The research was done in hindsight, using eggs that had been frozen, then thawed, so it could not draw watertight conclusions. “Ideally, these findings should be replicated in other sites with different conditions and different treatment protocols to confirm the findings,” Dr Leathersich said. “It would also be interesting to look at the impact of season and environmental factors on sperm parameters, as this could have contributed to our observations.” He added: “We are now planning to analyse this same group of patients using air quality data, as there may be seasonal changes in exposure to harmful pollutants which could negatively affect reproductive outcomes. “Finally, given the huge increase in so-called 'social egg freezing' for fertility preservation and the fact that this group generally have flexibility about when they choose to undergo treatment, it would be very interesting to see if these observations hold true with frozen eggs that are thawed and fertilised years later. “Any improved outcomes in this group could have big impacts for women making decisions about their future fertility, but the long-term follow-up required means it is likely to be some time before we can draw any conclusions for this population.” Have your say in our news democracy. 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Nearly a fifth of parents fear children will ignore health issues while at university
Nearly a fifth of parents fear their teenager will ignore a health issue while at university, as many self-diagnose on Google, research has found. Just 13 per cent of the 2,000 parents polled think their son or daughter would consult a proper doctor as soon as they feel unwell. More than one in 10 (12 per cent) think their offspring would be too lazy to seek medical attention, and 11 per cent fear they do not make their health a priority. The study of parents whose children either attend university, have done in the past or plan to soon, by Bupa Family+, also found that many (53 per cent) said their child thinks they are ‘invincible’ and nothing bad will ever happen to them. And as thousands of students prepare to start university, 56 per cent of parents feel excited for their child while 41 per cent are anxious. Dr Naveen Puri, GP and spokesperson for Bupa Family+, which commissioned the research to support the launch of its Family+ insurance proposition built around savings on health insurance for families, said: “All parents worry about their children, whatever their age. “But it can be especially difficult when they move out for the first time and become more independent – and you are no longer nearby to help them. “As a child and even a young adult, when you are unwell or have a health issue, your parents are often your first port of call, or even the ones spotting something is wrong in the first place. “They are usually the ones pointing you in the right direction, sorting appointments and arranging medication you might need. “Moving out or going to university is both an exciting and daunting time for all the family and we hope our new Family+ cover, which also insures older children, will help provide peace of mind to parents and their children alike.” It also emerged that parents’ top fears for their children as they embark on life away from the family home include their financial situation (44 per cent), their mental health (43 per cent), and whether they will be lonely (43 per cent). Others worry about who they will be spending time with (31 per cent), if they’ll know how to look after themselves (32 per cent) and what they’ll do when they feel unwell (23 per cent). And 64 per cent of those who have a child who has already left home admitted they have even lost sleep worrying about them. It emerged that 55 per cent think they would still be the first port of call for help or advice if their child felt unwell despite no longer living under the same roof. Ahead of them moving out, 63 per cent of parents will teach them how to manage their finances, while 59 per cent give tips on how to cook healthy meals. Others show their child how to use a washing machine (56 per cent), how to drink responsibly (40 per cent) and how to deal with mental health concerns (43 per cent). The study, carried out via OnePoll, also revealed girls are considered more likely to take care of their physical (43 per cent) and mental (41 per cent) health than boys (13 per cent and 11 per cent). Dr Naveen Puri, GP and spokesperson for Bupa Family+ said: “Our health is so important, and it can be worrying for parents that their child may be unwell when they aren’t there to help. “Making sure they have the knowledge about what to do in different health situations is a great way of not only ensuring they can look after themselves but also allows you to relax a little knowing they have the tools they need.” Here are the top reasons why parents worry their child would ignore health issues: 1. Googling and self-diagnosing 2. Being too lazy 3. Health is not a priority 4. Embarrassed to talk about their health 5. Worried a GP would judge them Read More ‘It can be hard when your kids leave the nest,’ mother says as study finds parents want their children back How to cope with anxiety during university How often should you wash your pyjamas? ‘My baby’s blue eyes drew praise – but their colour was a warning sign’ Brits get itchy feet in their home after five years, study finds
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Amy Schumer reveals she tried Ozempic while calling out celebrities for not being ‘real’ about weight loss
Amy Schumer has opened up about the reason why she stopped taking Ozempic, as she urged celebrities to be honest about their weight loss. The 43-year-old actor and comedian appeared on Watch What Happens Live with Andy Cohen on Thursday (8 June), where she revealed that tried taking the type 2 diabetes drug Ozempic for weight loss last year. “Like a year ago, I tried it,” she told Cohen, before admitting that she stopped taking the FDA-approved medication because of its side effects. “I was one of those people that felt so sick and couldn’t play with my son,” Schumer explained, referring to her four-year-old son Gene, who she shares with husband Chris Fischer. “I was so skinny and he’s throwing a ball at me and [I couldn’t].” Although the Trainwreck star admitted that she was “immediately invested” before trying the drug, she ultimately decided that Ozempic wasn’t “livable” for her. However, Schumer did take a moment to call out celebrities who have been “lying” about taking the once-weekly antidiabetic injection for weight loss. “Everyone’s like: ‘Smaller portions,’” she joked. “Shut the f*** up. You’re on Ozempic, or one of those things.” Much like Ozempic, FDA-approved medications Wegovy and Mounjaro are also brand names for semaglutide – which work by mimicking a hormone that regulates appetite and creates the feeling of fullness. “Just stop,” Schumer added. “Just be real with the people.” The Inside Amy Schumer star even noted how she was open about undergoing liposuction for weight loss in January 2022. “When I got lipo, I was like, I got lipo,” she said. Ozempic, a once-weekly injection used for the treatment of type 2 diabetes, has skyrocketed in use after people were reportedly prescribed the diabetes medication as an “off-label” weight loss drug. Meanwhile, Wegovy and Mounjaro are once-weekly semaglutide injections specifically approved for the treatment of obesity and weight loss. There are many side effects of taking medications like Ozempic, Wegovy, and Mounjaro. According to the US Food and Drug Administration (FDA), the most common side effects of taking Wegovy include nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, and digestive disorders. The FDA has also warned against more serious complications that can occur from using Wegovy or Mounjaro, such as the “potential risk of thyroid C-cell tumours,” pancreatitis, gallbladder problems, acute kidney injury, increased heart rate, and suicidal behaviour or thinking. Meanwhile, taking Ozempic can lead to possible thyroid tumours, including cancer, pancreatitis, changes in vision, and kidney and gallbladder problems. Amy Schumer isn’t the only celebrity to open up about taking certain medications for weight loss. Comedian Chelsea Handler previously revealed that she “didn’t know” she was on Ozempic because her doctor allegedly “hands it out to anybody”. During an appearance on Alex Cooper’s Call Her Daddy podcast in January, the Chelsea Lately star spoke candidly about the alleged widespread use of Ozempic in Hollywood and her concerns over its popularity. “So, my anti-ageing doctor just hands it out to anybody,” Handler claimed. “I didn’t even know I was on it. She said: ‘If you ever want to drop five pounds, this is good.’” She said she realised she was taking the type 2 diabetes drug for weight loss after feeling nauseous while at lunch with a friend, who was also on Ozempic. When her friend asked if Handler was taking the medication, which the comedian referred to as “semaglutide” during their conversation, her friend informed her Ozempic was simply a brand name for semaglutide. However, Handler said she stopped taking the medication after she realised what it was. “I’m not on it anymore. That’s too irresponsible,” she shared. “I’m an irresponsible drug user, but I’m not gonna take a diabetic drug. I tried it, and I’m not gonna do that. That’s not for me. That’s not right for me.” Read More Vanderpump Rules star Brittany Cartwright addresses rumours she’s taking Ozempic for weight loss FDA warns against using off-brand versions of Ozempic, Wegovy for weight loss Mark Wahlberg says he prefers to stay in shape ‘the old-fashioned way’ as he weighs in on Ozempic trend Debate sparker over parent who wouldn’t give her daughter any birthday cake Everything you need to know about hay fever How to protect pets from wildfire smoke amid air quality alert
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