The other night, I found myself with a Terrible, Horrible, No Good, Very Bad sunburn (as the fabled Alexander would put it). Now, a burn is painful enough on its own, but — as I learned — it’s especially bad at night. As I tucked myself into bed, sinking into what suddenly felt like sheets made of sandpaper, my skin screamed.

NEW YORK (AP) — Christian Siriano marked 15 years in business Friday with Sia performing on his runway and a nostalgic, ballet-inspired fantasy on his models during New York Fashion Week.

Almost 300 babies are born in the UK with sickle cells every year, according to the Sickle Cell Society, and the effects of sickle cell disease are believed to impact thousands. Yet, many people may not even know what sickle cells are or what living with the condition means. What is sickle cell disease? In most people, red blood cells are disc shaped and move easily through the blood vessels. But if you have sickle cell disease, your red blood cells are shaped like a sickle (similar to a crescent moon). This stops them moving with ease through the body and blood flow becomes restricted. Sickle cell disease isn’t actually one specific disease – it refers to a group of conditions affecting people with sickle cells, which range in severity.The conditions are inherited and predominantly affect people from African and Caribbean family backgrounds. What are the symptoms of sickle cell disease? Symptoms begin early in childhood and can sometimes be debilitating. How each individual is affected may vary, but the main symptoms are anaemia, an increased risk of infections, and pain. This includes extremely painful episodes called ‘sickle cell crisis’, which happens when blood flow to certain parts of the body become blocked. According to the NHS, these episodes can last for days and require hospitalisation. Other issues are associated with the condition too, including problems with the lungs, delayed growth in childhood, higher risk of stroke, leg ulcers and sight/vision problems.How is it diagnosed? Sickle cell disease is usually picked up during pregnancy or shortly after birth, although a blood test can be given at any time to see if someone has the condition or carries sickle cell genes. In parts of the country, pregnant people will be offered a test to see what the chances are of their child having sickle cells. Infants can be checked for the cells through a heel prick test.How do you treat it? Treating sickle cell disease is usually a lifelong process to help people with pain and to stay as healthy as possible. Treatment takes place in specific sickle cell centres and those living with it are encouraged to take care of their health, no matter the severity of their symptoms. Managing pain is a huge part of treating sickle cell disease. Staying hydrated can be helpful, as well as avoiding sudden temperature changes, like getting into a cold shower or diving into water. According to the NHS, Hydroxycarbamide (hydroxyurea) may be recommended, which is taken as a pill once a day. This can lower the quantity of other blood cells and requires careful monitoring, however. Some people may also be able to have a medicine called crizanlizumab, either on its own or alongside hydroxycarbamide, usually injected into a vein every four weeks. To prevent infections, many people with sickle cell disease will take daily antibiotics. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live TikTok has gone wild for adult gymnastics – here’s what you should know Man explains why he swapped veganism for raw meat diet: ‘I feel great’ Rugby star Ugo Monye: Boarding school shaped my career and my personality

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Aldi opened its 1,000th UK store on Thursday and committed to a further 500 outlets in the country

TL;DR: A one-year subscription to the CrossOver+ Windows Compatibility App is on sale for £40.46,

Senate Minority Leader Mitch McConnell spoke Saturday at the Fancy Farm picnic, one of Kentucky's classic political events, but his remarks were largely drowned out by jeers from the Democratic side of the crowd, who stomped their feet and yelled, "RETIRE," and "DITCH MITCH" as he spoke.

U.S. metropolitan areas are increasing in population again, growing by almost half a percent last year

When Evil Lurks' teaser trailer has arrived, offering a glimpse at the upcoming rural horror

It’s Saturday night, and DJ Laylo, one of my favorite DJs, is playing at Rumors in San Juan, Puerto Rico. I’ve been waiting for this party for weeks, so of course I planned my outfit ahead of time: a white, silky, strappy mini dress, black chunky knee-high boots, and my hair in a messy pony. I’m going for grungy but sexy vibes — think Bride of Chucky‘s Tiffany Valentine. I roll on my favorite vanilla essential oil and I’m ready to go.

Felipe Massa’s lawyers have started legal action against Formula 1 and the FIA over the 2008 F1 title loss to Lewis Hamilton, seeking substantial damages following that year’s “Crashgate” scandal. Lawyers acting on Massa’s behalf allege that the former Ferrari driver has been “the victim of a conspiracy committed by individuals at the highest level of F1 together with the FIA and Formula One management.” Massa missed out on the 2008 title in dramatic circumstances at the final race in Brazil as Hamilton – then driving for McLaren - claimed the point he needed on the final lap in wet conditions. “Crashgate” rocked the sport when the inaugural Singapore Grand Prix saw Renault’s Fernando Alonso win the race before it emerged that his team-mate Nelson Piquet Jr. had deliberately crashed to bring out a safety car that played into Alonso’s hands. That safety car prompted a Massa pit stop that Ferrari mishandled, with Massa eventually finishing the race 13th while Hamilton came home third. Read More ITV descends into chaos as ‘psychic parrot’ predicts winner of World Cup final Borthwick hits out at ‘personal attacks’ against Farrell ahead of Rugby World Cup Spectator imitating bee disturbs tennis player mid-match

Elizabeth Hurley has issued a reminder to women about getting mammograms, in honour of her partnership with Estée Lauder’s Breast Cancer Awareness campaign. The model, 58, spoke candidly about mammograms – which are X-rays performed on women’s breasts to screen for cancer – during a recent interview withUs Weekly. While discussing her last 28 years as the ambassador of Estée Lauder’s campaign, she told women that if they feel something “abnormal” when examining their bodies, they shouldn’t hesitate to get it checked by a doctor. “I think the most important thing you can do is familiarise yourself with your breasts because they’re yours and only you know how they feel,” she said. “You should recognise something when it’s abnormal, and you should go to the doctor right away.” Hurley emphasised that annual screenings for breast cancer are not only “vital,” but they should be considered a part of “looking after your health in every way”. She also went on to urge women to be “breast cancer bullies” by continuing to encourage their loved ones to get checked for the disease. “Make sure your friends, your family, your mother, your grandmother, that they’re going for their screenings regularly and urge them to self-check,” she said. “It doesn’t discriminate. It can hit anybody. Some groups are more vulnerable than others.” She also made a reference to one breast cancer that can be difficult to treat, triple-negative breast cancer, which “differs from other types of invasive breast cancer” because “it tends to grow and spread faster, has fewer treatment options, and tends to have a worse prognosis”, as noted by the American Cancer Society. The type of cancer can also be “more common in women younger than age 40, who are Black, or who have a BRCA1 mutation”. “It disproportionately affects Black women,” the Bedazzled star added. “It’s a diverse disease and it needs to be attacked in a diverse way.” According to the American Cancer Society, women between the ages of 45 and 54 “should get mammograms every year”. Meanwhile, women who are 55 and older can either “switch to a mammogram every other year, or they can choose to continue yearly mammograms”. In addition, women between the ages of 40 and 44 “have the option to start screening with a mammogram every year”. The organisation also noted that breast cancer is the most common cancer in women, with estimates of “about 297,790 new cases of invasive breast cancer” being diagnosed in women in the US in 2023. Over the years, Hurley has continued to speak about the importance of getting a mammogram. Last year, she joined Loose Women hosts Kaye Adams, Brenda Edwards, Nadia Sawalha, and Carol McGiffin for a self-examination on live TV. During the segment, she also opened up about losing her own grandmother to the disease, and how her attitudes towards breast cancer have shifted over time. “At that time nobody talked about it. There was no pink ribbon, no Breast Cancer Awareness month,” the Serving Sara star said, adding that when her grandmother first found a lump in her breast, she didn’t go to the doctor because she was “scared and embarrassed”. “When she finally went it was quite progressed. But she still never talked about it,” the model continued. “It’s still a life-threatening disease for many women, but times have changed. We talk about it now.” During her interview with Us Weekly, she went on to celebrate her 28th year with Estée Lauder’s Breast Cancer Awareness campaign, noting that Estée Lauder’s daughter-in-law, Evelyn Lauder, is the one who first asked her “to get involved” with the mission. “That’s how it started, and I’m still here. We’ve raised $118m, 93 million of which went straight to research,” she said. “The rest went to education, medical services, support groups [and more]. It’s a phenomenal achievement.” Read More Big Brother narrator Marcus Bentley: Meet the man behind TV’s most recognisable voice ‘Not guilty’: Elizabeth Hurley reacts to rumours she took Prince Harry’s virginity Elizabeth Hurley slams British Airways’ ‘dodgy service’ after getting stuck in Antigua Like Sophie Anderton, I have felt the shame of struggling to have a child of my own How to spot if your child is struggling with their mental health – and what to do next How to get rid of bedbugs: Signs and symptoms amid threat of UK invasion